It took a terribly ordinary story, told repeatedly in thousands of soap operas, and frames it in the language of video games, turning it into something quite extraordinary.
It doesn't help that the entire cast is made of awesome, particularly Kieran Culkin and Jason Schwartzman. Michael Cera is probably perfectly suited for playing Scott, because (like the comic book) I spent most of the film wanting to slap him repeatedly with a wet fish. And Mary Elizabeth Winstead is effortlessly cool.
If you're at all geeky then go see it. Julie and I both enjoyed it an awful lot.